Waifu2x-Extension-GUI is a C++ desktop application that leverages deep convolutional neural networks to upscale and enhance images, GIFs, and videos. It wraps multiple neural network models including Waifu2x, Real-ESRGAN, Real-CUGAN, and frame interpolation models like RIFE, IFRNet, CAIN, and DAIN. The application provides GPU acceleration support for AMD, Nvidia, and Intel GPUs and includes settings presets for one-click configuration.